Each order of AndroNorth Telmisartan Tablets contains one (1) satchet of sixty (60) tablets, each containing 40mg of highly pure Telmisartan.
Telmisartan is a pharmaceutical compound classified as an angiotensin II receptor blocker (ARB), primarily used in the management of high blood pressure (hypertension) and cardiovascular risk. It works by selectively blocking the angiotensin II type 1 (AT1) receptor, which plays a central role in regulating blood pressure, fluid balance, and vascular resistance.
By inhibiting the action of angiotensin II, telmisartan promotes vasodilation (widening of blood vessels) and reduces the release of aldosterone, a hormone involved in sodium and water retention. This results in lower blood pressure, decreased strain on the heart, and improved overall cardiovascular function.
In addition to its antihypertensive effects, telmisartan has unique metabolic properties compared to other ARBs. It exhibits partial activation of peroxisome proliferator-activated receptor gamma (PPAR-γ), a nuclear receptor involved in glucose and lipid metabolism. This activity has led to interest in telmisartan for potential benefits related to insulin sensitivity and metabolic health.
Telmisartan is characterized by a long half-life, allowing for once-daily oral dosing and consistent 24-hour blood pressure control. Its high lipid solubility also supports effective tissue penetration, contributing to sustained therapeutic activity.
Telmisartan tablets are formulated for convenient oral administration and are widely used in clinical practice for the treatment of hypertension and for reducing the risk of cardiovascular events in high-risk individuals. Ongoing research continues to explore its broader applications in metabolic and renal health.
Key Points
Action:
Blocks angiotensin II type 1 receptors to promote vasodilation, reduce aldosterone secretion, and lower blood pressure.
Indications:
Used in the treatment of hypertension and in reducing cardiovascular risk; studied for potential metabolic benefits.
Difference from Other ARBs:
Telmisartan has a longer half-life and partial PPAR-γ activity, which may offer additional metabolic advantages compared to similar medications.
